Download e-book for iPad: Sweetness and Sweeteners. Biology, Chemistry, and by Deepthi K. Weerasinghe, Grant DuBois
By Deepthi K. Weerasinghe, Grant DuBois
content material: Sweetness and sweeteners: what's the entire pleasure approximately? / supply E. DuBois --
Genetic structure of candy style / Alexander A. Bachmanov --
Making experience of the candy flavor receptor / Peihua Jiang ... [et al.] --
T1R2, T1R3, and the detection of candy stimuli / Stephan Vigues ... [et al.] --
In vitro versions to review style: can sweetness be modeled in a dish? / Nancy E. Rawson and M. Hakan Ozdener --
Structure-activity dating and AH-B after forty years / Terry E. Acree and Michael Lindley --
Crystal buildings of the candy protein MNEI: insights into candy protein-receptor interactions / Jeanette R. Hobbs, Steven D. Munger, and Graeme L. Conn --
Molecular versions of candy style receptors offer insights into functionality / Meng Cui ... [et al.] --
Pharmacophore modeling of candy and sour tasting molecules / Nicolas Froloff --
a number of receptors or a number of websites? Modeling the human T1R2-T1R3 candy style receptor / Gabriella Morini, Angela Bassoli, and Piero A. Temussi --
Computational docking to candy style receptor types / D. Eric Walters --
What can psychophysical experiences with sweetness inhibitors train us approximately style? / Veronica Galindo-Cuspinera and Paul A.S. Breslin --
a mode to degree flavor features, flavor depth, and temporal profile of compounds geared toward human intake by means of style nerve recordings in monkeys / Göran Hellekant and Yiwen Wang --
The bittersweet look for bitter-sweet interactions: mobile to phone communique within the soft palate / M. Scott Herness, Fang-li Zhao, and Yu Cao --
cAMP: a job in candy style version / Nirupa Chaudhari and Sue C. Kinnamon --
Saccharin: man made sweetener, sour tastant, and candy style inhibitor / Marcel Winnig ... [et al.] --
Permeation of amphipathic sweeteners into taste-bud cells and their interactions with post-receptor signaling parts: attainable implications for sweet-taste caliber / M. Naim ... [et al.] --
we're what we devour, yet why? Relationships among oral sensation, genetics, pathology, and vitamin / Derek J. Snyder ... [et al.] --
notion and recognition of sweeteners / Jeannine F. Delwiche and Amanda R. Warnock --
Interindividual alterations of flavor sensitivity in people and hamsters: a number of receptor websites for unmarried natural molecules / Annick Faurion --
The "bitter candy" fact of synthetic sweeteners / C.T. Simons ... [et al.] --
using rodent versions to hyperlink neurobiological techniques with the psychophysics of candy flavor / A.C. Spector, S. Eylam, and C.D. Dotson --
useful characterization of the human candy style receptor: excessive- throughput screening assay improvement and structural functionality relation --
Xiaodong Li and man Servant --
improvement of temporary receptor power melanostation five modulators for sweetness enhancement / R.W. Bryant ... [et al.] --
Enhancers for candy style from the area of non-volatiles: polyphenols as flavor modifiers / Jakob P. Ley ... [et al.] --
assessment of high-intensity sweetener modulators / Cheryl R. Mitchell, Richard Ray, and Marian Schwartz --
enhancing the style of synthetic sweeteners utilizing flavors / Masashi Ishikawa ... [et al.] --
Why should still on natural chemist research candy flavor? / Angela Bassoli ... [et al.] --
Sweeteners and beauty modulators: requisites for advertisement viability / furnish E. DuBois --
improvement of recent, low calorie sweetener: new aspartame by-product / Yusuke Amino ... [et al.] --
demanding situations to decreasing sugar in meals / D. Kilcast, C. den Ridder, and C. Narain --
improvement of a brand new, no calorie advertisement sweetener neotame / Indra Prakash and Ihab E. Bishay --
Sensory homes of neotame: comparability with different sweeteners / Susan S. Schiffman, Elizabeth A. Sattely-Miller, and Ihab E. Bishay --
contemporary advancements in structure-taste stories of sulfamates / William J. Spillane ... [et al.] --
Neoculin as a brand new protein with taste-modifying job: purification, characterization, and X-ray crystallography / A. Shimizu-Ibuka ... [et al.] --
How candy it truly is: distinctive molecular and practical experiences of brazzein, a candy protein and its analogs / Fariba Assadi-Porter ... [et al.] --
Steviol glucuronide as excretion fabricated from stevioside in human volunteers: loss of carcinogenic homes of steviol glycosides and steviol / Jan M.C. Geuns --
Stevioside: a secure sweetener and attainable new drug for the therapy of the metabolic syndrome / Jan M.C. Geuns.
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Additional resources for Sweetness and Sweeteners. Biology, Chemistry, and Psychophysics
Journal of Dental Research 1997, 76, 831 -838. ; ACS Symposium Series; American Chemical Society: Washington, DC, 2008. ch002 43 87. uk/nomenclature/. 88. shtml. 89. Hoon, Μ. ; Battey, J. ; Ryba, N. ; Zuker, C . S. Cell 1999, 96, 541-551. 90. Bachmanov, Α. ; Reed, D. ; Ohmen, J. ; Tordoff, M . ; de Jong, P. ; West, D. ; Ross, D. ; Beauchamp, G . K. Chem. Senses 2001, 26, 925-933. 91. L i , X . ; Bachmanov, Α. ; Tordoff, M. G . ; Beauchamp, G . K . ; de Jong, P. ; Chen, L . ; West, D . B . ; Ross, D.
Dots indicate marker content of the BAC clones. e. Genes within the Sac-containing interval. Filled areas indicate predicted genes. Arrows indicate the predicted direction of transcription. Reproduced with permission from reference (93). Copyright 2002. ; ACS Symposium Series; American Chemical Society: Washington, DC, 2008. ch002 80 • w 70 60 8 ooo 50 ο ο ο 40 1 +179 Τ +179 C Figure 2. 6 mM saccharin by mice from inbred strains with different Taslr 3 genotypes at the T/C variant site at nucleotide position +179 (relative to the first nucleotide in the A TG start codon of the Taslr3 gene).
ACS Symposium Series; American Chemical Society: Washington, DC, 2008. ch002 32 a large number of sweeteners (Table II). The in vitro system reproduces in vivo species differences in sweet taste sensitivity. , (65, 69, 141)). Correspondingly, human but not rodent T1R2 + T1R3 responds to these sweeteners in vivo. The ligand specificity of human T1R2 was also examined in vivo using Taslr2 knockout mice that express a human TAS1R2 transgene under control of mouse Taslr2 promoter. While wild-type mice are indifferent to aspartame, glycyrrhizic acid, thaumatin and monellin, the transgenic mice display appetitive responses to these stimuli (96).
Sweetness and Sweeteners. Biology, Chemistry, and Psychophysics by Deepthi K. Weerasinghe, Grant DuBois