Get Issues and Reviews in Teratology: Volume 7 PDF
By Dick Smithells (auth.), Harold Kalter (eds.)
From a overview of an past quantity: 'Both the experimental and the human facets of teratology are awarded during this accomplished textual content by way of a stellar team of across the world famous scientists and clinicians....A worthy source for these thinking about experimental teratology and chance evaluation and people requiring normal information regarding the motives of delivery defects. The remedy of those concerns is subtle, succinct, and logical.'-American Scientist
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Extra resources for Issues and Reviews in Teratology: Volume 7
I Laboratories are ese>ential for exploring ideas, but the most hopeful place for generating ideas about the prevention of birth defects is the maternity unit, and the people best placed to generate the m are those who examine babies and listen to mothers. ) and nothing could be done about them. Now we have enough tools and strategies to make a small impression. Obstetricians and paediatricians (nurses and midwives, too) must be educated to think positively about a problem that affects more than 2 per cent of all babies born.
1993) in pregnant epileptic women receiving CBZ alone or in combination with other anticonvulsants. The results were compared with pregnancy outcome in a prospective cohort. Drug and metabolite levels were evaluated in 115 of the 159 pregnancies: CBZ 10-11 epoxide serum levels increased with increasing CBZ dose. Phenobarbital given together with CBZ reduced the levels compared with when CBZ was given in monotherapy, but valproic acid increased them. Valproic acid may increase CBZ epoxide levels by inhibition of detoxifying enzymes such as epoxide hydratase.
Lancet 1:1095-97. , Sheppard. J. and Wild, J. 1983 Further experience of vitamin supplementation for the prevention of neural tube defect recurrences. Lancet 1:1027-1031. W. H. 1992 The 28 recognition of thalidomide defects. J. med. Genet. 29:716-723. W. B. 1959 Congenital heart block. Arch. Dis. Childh. 34:223-227. W. and Sheppard, S. 1978 Teratogenicity testing in humans: A method demonstrating safety of Bendectin. Teratology 17:31-36. , Sheppard, S. J. 1976 Vitamin deficiencies and neural tube defects.
Issues and Reviews in Teratology: Volume 7 by Dick Smithells (auth.), Harold Kalter (eds.)