Search TXNP
txnp temp ad

< More Press Releases

Saturday, February 25, 2017

Share: facebooktwitterdigg

UTSA Alumna, Advisors Launch Cardiovate to Offer Surgeons New Stent-Graft to Prevent Aortic Aneurysm Rupture
UTSA

May, 2012

University of Texas at San Antonio (UTSA) alumna Jordan Kaufmann, Ph.D., UTSA College of Engineering Dean Mauli Agrawal and UT Medicine San Antonio cardiologist Steven Bailey, M.D. have launched Cardiovate, a technology start-up that will offer a new and much-needed cardiovascular stent-graft to prevent aneurysm leakage following cardiovascular surgeries.

 

 

Kaufmann, an alumna of the UTSA College of Engineering’s Department of Biomedical Engineering, developed the stent-graft as part of her doctoral research with UTSA’s Agrawal and Bailey, division chief for cardiology in the School of Medicine of The University of Texas Health Science Center at San Antonio.

 

 

“To take an idea that we were throwing around and develop it all the way to a product for a start-up company has been an incredible opportunity,” said Kaufmann. “The path epitomized both translational research and multidisciplinary studies, which has been a great educational experience.”

 

 

Approximately 1.2 million people in the U.S. suffer from an abdominal aortic aneurysm. Aneurysm rupture is the nation’s 13th leading cause of death. Surgeons perform about 65,000 abdominal aortic aneurysm repairs annually.

 

 

However, in a surgical repair procedure called Endovascular Aneurysm Repair, one out of every six patients experiences stent-graft leakage from traditional stent-grafts in the month following surgery. Additionally, 20 to 30 percent of patients require an additional corrective surgery as much as six to eight years later.

 

 

            While pursuing her doctoral degree in biomedical engineering at UTSA under the supervision of Agrawal and Bailey, Kaufmann developed a unique scaffold which promotes tissue formation. The product, called a tissue engineering scaffold for aneurysm repair (TESAR), creates a tissue barrier between the blood and the aneurysm after it is implanted. The scaffold promotes healthy tissue formation to repave the aneurysm wall. Once the scaffold is in place, the aneurysm stops expanding and the risk of rupture decreases. After new tissue is in place, the scaffold degrades and is safely reabsorbed by the body.

 

 

            Cardiovate’s TESAR stent-graft has been shown in the laboratory to reduce post-operative complications during aneurysm repair surgery such as the need for additional corrective surgeries following the initial procedure. Also, the natural tissue is a better match for biological healing than the materials found in traditional stent-grafts.

 

 

Between now and March 2013, Kaufmann, Agrawal and Bailey will work together to refine the manufacturing of the TESAR, and they will test it to ensure it conforms to the highest safety and quality standards.

 

 

“The launch of Cardiovate is testament to the phenomenal technology being created in UTSA labs and the great entrepreneurial ecosystem the university fosters” said Cory Hallam, director of the UTSA Center for Innovation and Technology Entrepreneurship. “These types of spin-offs have the ability to save lives, create jobs, build multi-million dollar markets and significantly reduce health care costs caused by complications that arise with the existing technologies.”

 

 

The scholars expect to make the product available for licensing to a larger company in 2013. It would then ideally be on the market for vascular surgeons to use shortly after being evaluated by the FDA.

 

 

------------------------------

 

 

 

 

The University of Texas at San Antonio is one of the largest of nine academic universities and six health institutions in the UT System. As a multicultural institution of access and excellence, UTSA aims to be a national research university providing access to educational excellence and preparing citizen leaders for the global environment.

 

 

UTSA serves nearly 31,000 students in more than 135 degree programs in the colleges of Architecture, Business, Education and Human Development, Engineering, Honors, Liberal and Fine Arts, Public Policy, Sciences and the Graduate School. Founded in 1969, UTSA is an intellectual and creative resource center and a socioeconomic development catalyst for Texas and beyond. Learn more atwww.utsa.edu.



rss 

Your TXNP Weekly E-Newsletter is made possible by the generosity of:

FROST in many Texas cities
THE SID RICHARDSON FOUNDATION in Fort Worth




TXNP Professional Members Are Dedicated to Texas and Texans.

Aurora Grants & Consulting |Dawson Murray Teague Communications | ELITE Research | FOR THE PHILANTHROPIST | Graystone Consulting | J A Churchill Associates | John F. Lewis PC | McConnell & Jones LLC





Sign up for your personal TXNP E-Newsletter

at-t Meadows Foundation express news HOBLITZELLE FOUNDATION v greenly zachry foundation w b h b bank of america southwest airlines Sid W. Richardson Foundation forst